Selected Publications

2007

Jean-Noel Billaud, Darrell Peterson, Byung O. Lee, Toshiyuki Maruyama, Antony Chen, Matti Sallberg, Fermin Garduno, Phillip Goldstein, Janice Hughes, Joyce Jones and David Milich. Advantages to the Use of Rodent Hepadnavirus Core Proteins as Vaccine Platforms. Vaccine 2007; 25(9):1593-606.

Jean-Noel Billaud, Darrell Peterson, Florian Schodel, Antony Chen, Matti Sallberg, Fermin Garduno, Phillip Goldstein, Wendy McDowell, Janice Hughes, Joyce Jones, and David Milich. Comparative Antigenticity and Immunogenicity of Hepadnavirus Core Proteins. J of Virol. 2005; 79:13641-13655.
Jean-Noel Billaud, Darrell Peterson, Margaret Barr, Antony Chen, Matti Sallberg, Fermin Garduno, Phillip Goldstein, Wendy McDowell, Janice Hughes, Joyce Jones, and David Milich. Combinatorial Approach to Hepadnavirus-Like Particle Vaccine Design. J of Virol. 2005; 79:13656-13666.
Margaret T. Chen, Matti Sallberg, Janice Hughes, Joyce Jones, Luca G. Guidotti, Francis V. Chisari, Jean-Noel Billaud, and David R. Milich. Immune Tolerance Split between the Hepatitis B Virus Precore and Core Proteins. J of Virol. 2005; 79:3016-3027.
Byung O. Lee, Javier Rangel-Moreno, Juan E. Moyron-Quiroz, Louise Hartson, Melissa Makris, Frank Sprague, Frances E. Lund and Troy d. Randall. CD4 T Cell-Independent Antibody Response promotes Resolution of primary influenza infection and Helps to Prevent Reinfection. J of Imm. 2005; 175:5827-38.

Margaret T. Chen, Jean-Noel Billaud, Matti Sallberg, Luca G. Guidotti, Francis V. Chisari, Joyce Jones, Janice Hughes, and David R. Milich. A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen. PNAS 2004; 101:14913-14918.

Lee, BO, Hartson,OL, Randall TD. CD40-deficient, influenza-specific CD8 memory T cells develop and function normally in a CD40-sufficient environment. J. Exp. Med. 2003; 198:1759-64.
Lee BO, Moyron-Quiroz J, Rangel-Moreno J, Kusser KL, Hartson L, Sprague F, Lund FE, Randall TD. CD40, but not CD154, expression on B cells is necessary for optimal primary B cell response. J. of Imm. 2003; 171:5705-17.

Byung O. Lee, Laura Haynes, Sheri M. Eaton, Susan l. Swain and Troy D. Randall. The biological Outcome of CD40 Signaling is Dependent on the Duration of CD40 Lignad Expression: Reciprocal Regulation by Interleukin (IL)-4 and IL-12. J. Exp. Med. 2002; 196:693-704.
Chen M, Sallberg M, Thung SN, Hughes J, Jones J, Milich DR. Modeling the T helper cell response in acute and chronic HBV infection using T cell receptor transgenic mice. Antiviral Research 2002; 52:99-111.
Milich DR. Influence of C4A deficiency on non-response to HBsAg vaccination: A new immune response gene. J of Hepatol. 2002; 37:396-399.

Lazdina U, Cao T, Steinbergs J, Alhein M, Pumpens P, Peterson DL, Milich DR, Leroux-Roels G, Sallberg M. Molecular basis for the interaction of the hepatitis B core antigen with the surface Ig receptor on naïve B cells. J of Virol. 2001; 75:6367-6374.
Cao T, Lazdina U, Desombrer I, Vanlandschoot P, Milich DR, Sallberg M, Lerouz-Roels G. The hepatitis B virus core antigen binds and activates naïve human B cells in vivo-studies in a human PBL-NOD/SCID mouse model. J of Virol. 2001; 75:6359-6366.
Milich DR, Hughes J, Jones J, Sallberg M, Phillips TR. Conversion of poorly immunogenic malaria repeat sequences into a highly immunogenic vaccine candidate. Vaccine 2001; 20:771-788.

Chen M, Sallberg M, Thung SN, Hughes J, Jones J, Milich DR. Nondeletional T-cell receptor transgenic mice: model for the CD4(+) T-cell repertoire in chronic hepatitis B virus infection. J of Virol. 2000; 74:7587-7599.
Billaud JN, Ly C, Phillips TR, de la Torre JC. Borna disease virus persistence causes inhibition of glutamate uptake by feline primary cortical astrocytes. J of Virol. 2000; 74:10438-10446.
Billaud JN, Selway D, Yu N, Phillips TR. Replication rate of feline immunodeficiency virus in astrocytes is envelope dependent: implications for glutamate uptake. Virology. 2000; 266:180-188.